Matrine
English name
Alternately known as bitter licorice, sophora flavescens, sophora root, western bean root, sophora root, wild locust root, mountain locust root, dried ginseng, and bitter bone.
Plant source: The dried roots of the leguminous plant Sophora flavescens.
Molecular formula
Molecular weight
Appearance: white needle-like or prismatic crystals or white powder, odorless and bitter
Detection method
Function and indication
Urinary effect: Matrine contained in Sophora flavescens decoction can produce diuretic effect when administered orally to rabbits. Before the urine output increases, there will be an increase in salt excretion. However, the number of rabbits used in the experiment was small, and the drinking water control was not described. Therefore, some people believe that further research is needed
The pathogen effect decoction has an inhibitory effect on Mycobacterium tuberculosis at high concentrations in the test tube. Decoctions and water decoctions have varying degrees of inhibitory effects on some common skin fungi in vitro
Other effects: When matrine was injected into rabbits, it was found that central nervous system paralysis, simultaneous spasm, and eventually respiratory arrest resulted. die. When injected into a frog, the frog is initially excited, then paralyzed, breathing becomes slow and irregular, and finally spasms, leading to respiratory arrest and death. The spasms are probably caused by spinal reflexes. The minimum lethal dose for rabbits is/kg.
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